Publications

  1. Agudo J, Park ES, Rose SA, Alibo E, Sweeney R, Dhainaut M, Kobayashi KS, Sachidanandam R, Baccarini A, Merad M, Brown BD. Quiescent Tissue Stem Cells Evade Immune Surveillance. Immunity 2018; Feb 20;48(2):271-285. [PubMed] [Article]
  2. Chia G, Agudo J, Treff N, Brown BD, Baer R, and Egli D. Genomic instability during reprogramming by nuclear transfer is replication dependent. Nature Cell Biology 2017; Apr;19(4):282-291. [PubMed] [Article]
  3. Agudo J, Brown BD. Silence of the ROS. Immunity. 2016 Mar 15;44(3):520-2. [PubMed] [Article]
  4. Salmon H, Idoyaga J, Rahman A, Leboeuf M, Remark R, Jordan S, Casanova-Acebes M, Khudoynazarova M, Agudo J, Rivera C, Hogstad B, Bosengerb M, Hashimoto D, Gnjatic S, Bhardwaj N, Palucka AK, Brown BD, Brody J, Ginhoux F, Merad M. CD103+ DC progenitor expansion and activation at the tumor site transforms clinical response to PD-L1 and BRAF inhibition. Immunity 2016; Apr 19;44(4):924-38.  [PubMed] [Article]
  5. Agudo J, Ruzo A, Park ES, Sweeney R, Kana V, Wu M, Zhao Y, Egli D, Merad M, Brown BD. GFP-specific CD8 T cells enable targeted cell depletion and visualization of T-cell interactions. Nature Biotechnology. 2015 Dec;33(12):1287-1292.​ [PubMed] [Article]
  6. Kidd B, Wroblewska A, Boland MR, Agudo J, Merad M, Tatonetti NP, Brown BD, and Dudley JT. Mapping the effects of drugs on the immune system. Nature Biotechnology 2015; Nov 30. doi: 10.1038/nbt.3367. [PubMed] [Article]
  7. Agudo J, Ruzo A, Tung N, Salmon H, Leboeuf M, Hashimoto D, Becker C, Garrett-Sinha LA, Baccarini A, Merad M, and Brown BD. The miR-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acids. Nature Immunology. 2014 Jan;15(1):54-62.  [PubMed] [Article]
  8. Israelow B, Mullokandov G, Agudo J, Sourisseau M, Bashir A, Maldonado AY, Dar AC, Brian D. Brown BD, Evans MJ. Hepatitis C virus genetics affects miR-122 requirements and response to miR-122 inhibitors. Nature Communications 2014; Nov 18;5:5408.  [PubMed] [Article]
  9. Agudo J, Ruzo A, Kitur K, Blander JM, Brown BD. A TLR and non-TLR mediated innate response to lentiviruses restricts hepatocyte entry and can be ameliorated by pharmacological blockade. Molecular Therapy. 2012 Dec;20(12):2257-67.  [PubMed] [Article]
  10. Agudo J, Salavert A, Ayuso E, Jiménez V, Casellas A, Ruzo A, Tafuro S, Ruberte J, and Bosch F. Increased VEGF expression in islets leads to altered insulin secretion and overt diabetes with age. Diabetes. 2012 Nov;61(11):2851-61.  [PubMed] [Article]
  11. Greter M, Helft J, Chow A, Hashimoto D, Mortha A, Agudo-Cantero J, Bogunovic M, Gautier EL, Miller J, Leboeuf M, Lu G, Aloman C, Brown BD, Pollard JW, Xiong H, Randolph GJ, Chipuk JE, Frenette PS, Merad M. GM-CSF Controls Nonlymphoid Tissue Dendritic Cell Homeostasis but Is Dispensable for the Differentiation of Inflammatory Dendritic Cells. Immunity 2012; Jun 29;36(6):1031-46.  [PubMed] [Article]
  12. Helft J, Manicassamy B, Guermonprez P, Hashimoto D, Silvin A, Agudo J, Brown BD, Schmolke M, Miller J, Murphy K, García-Sastre A, Merad M. Cross-presenting CD103+ dendritic cells are protected from influenza virus infection. Journal of Clinical Investigation 2012; Nov 1;122(11):4037-47. [PubMed] [Article]
  13. Agudo J*, Martin M*, Roca C, Molas M, Bura AS, Zimmer A, Bosch F, Maldonado R. Deficiency of CB2 cannabinoid receptor in mice improves insulin sensitivity but increases food intake and obesity with age. Diabetologia. 2010 Dec;53(12):2629-40.  [PubMed] [Article]
  14. Agudo J*, Ayuso E*, Jimenez V, Salavert A, Casellas A, Tafuro S, Haurigot V, Ruberte J, Segovia JC, Bueren J, Bosch F. IGF-I mediates regeneration of endocrine pancreas by increasing beta cell replication through cell cycle protein modulation in mice. Diabetologia. 2008 Oct;51(10):1862-72.  [PubMed] [Article]